Synthesis of Novel Cysteine Peptide Nucleic Acid (CPNA)

Many diseases are caused due to abnormalities in production of specific protein. Across this protein the conventional lock and key mechanism shows binding at the specific cites of protein. However use of antisense technology can prevent formation of protein. It does so by binding to mRNA and prevents transcription. The structural modifications lead to synthetic molecules with 18-mer units which show significant improvement in binding properties, this gives birth to a new class of oligomers called Peptide Nucleic Acid (PNA). We herein report cysteine based PNA called CPNA.

Grantor dc:publisher

Digital Commons @ University of South Florida

Year dc:date

2007

Author dc:creator

• Ajmera, Mehul J

• Antisense
• Antigene
• Antibacterial
• Antiviral
• Cytosine acetic acid
• American Studies
• Arts and Humanities

Statement dc:rights

• default

Repository record dc:identifier

https://digitalcommons.usf.edu/etd/112

OAI identifier oai:identifier

oai:digitalcommons.usf.edu:etd-1111