Effects of Daily Oral Injections of Quercetin on Implanted Colon-25 Tumor Growth in Balb-C Mice

The effects of three oral dosages (0.4 mg, 0.8 mg, and 1.6 mg) of quercetin on Colon-25 tumors implanted in Balb-c mice were studied. The data in this study show that: (1) certain dosages of quercetin in alcohol solutions, reduces the weight, and size of implanted Colon-25 tumors in Balb-c mice, (2) these same dosages of quercetin all produce a profound neutrophilia combined with a significant lymphopenia at day 20 post-implantation, and (3) there was relatively little evidence of histological changes in the quercetin-treated tumor section which would indicate that the action(s) of quercetin is primarily at the subcellular level probably within the nuclei of the tumor cells.

Grantor dc:publisher

University of North Texas

Year dc:date

2000

Author dc:creator

• Hayashi, Adam

Contributors dc:contributor

• Lott, James R.
• Schwark, Harris
• O'Donovan, Gerard A.

• Quercetin.
• Cancer -- Chemotherapy.
• Mice -- Diseases -- Chemotherapy.
• neutrophilia
• lymphopenia
• quercetin
• bioflavonoids
• mammalian tumors

Statement dc:rights

• Public
• Copyright
• Hayashi, Adam
• Copyright is held by the author, unless otherwise noted. All rights reserved.

Language dc:language

English

Identifier

oclc: 47163441
untcat: b2300394
https://digital.library.unt.edu/ark:/67531/metadc2525/
ark: ark:/67531/metadc2525

OAI identifier oai:identifier

info:ark/67531/metadc2525