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Showing 1 to 20 of 142 for “"quercetin"”.
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Relative systemische Verfügbarkeit und Pharmakokinetik von Quercetin und Quercetinglykosiden (Quercetin-4'-0-glucosid und Quercetin-3-0-rutinosid) im Menschen
… Wirkung wurde das Falvonol Quercetin in den letzten Jahren intensiv untersucht. Daten zur Bioverfuegbarkeit nach oraler Applikation sind jedoch selten und widerspruechlich. Fruehere Untersuchungen deuteten darauf hin, dass die Disposition von Quercetin von der …
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THE BIOSYNTHSIS OF QUERCETIN IN BUCKWHEAT
… A. C. Neish that this work, on the biogenesis of quercetin, one of the most widely distributed flavonols in nature, was undertaken. The glycoside rutin, which on hydrolysis yields quercetin, is obtained in relatively large quantities from buckwheat leaves.
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The effects of quercetin on iron metabolism
… cells were used to investigate the influence of quercetin, the most abundant flavonol in the diet, on non-haem iron bioavailability using 55Fe, and the gene expression of intestinal iron transporters as measured via qPCR.<br/>Chronic exposure to quercetin (24 hours) had no significant effect on …
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Amorphous solid dispersion effects on in vitro solution concentrations of quercetin
Quercetin is a flavonol with potential health benefits including activities against cardiovascular disease, obesity, and oxidative stress. However, the benefits of quercetin are likely limited by poor bioavailability, primarily attributed to its poor aqueous solubility (due to its hydrophobicity …
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Effects of Quercetin Supplementation on Physical and Mental Functions in Older Adults
… by certain nutraceuticals have intensified. Quercetin, known as a natural polyphenolic flavonoid substance found in variety of human foods, possesses multiple biological properties, in particular, the ability to stimulate mitochondrial biogenesis and reduce inflammation, form the basis for …
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Effects of 5-Fluorouracil Chemotherapy On Fatigue and Inflammation In Mice: Benefits of Quercetin
… on Fatigue and Inflammation in Mice: Benefits of Quercetin Cancer related fatigue is one of the most distressing symptoms reported by cancer patients, however little research has been done to elucidate the cause(s) of this debilitating condition. Because nearly all cancer patients undergo harsh …
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Einfluss des Flavonoids Quercetin auf die epitheliale Barrierefunktion der humanen Kolonkarzinom-Zelllinie Caco-2
… des am häufigsten vorkommenden Flavonoids Quercetin auf die Barrierefunktion der Kolonkarzinom-Zelllinie Caco-2 zu untersuchen. Hierbei zeigte sich, dass Quercetin konzentrationsabhängig (50-200 µM) den transepithelialen Widerstand erhöhte. Die Wirkung von 200 µM Quercetin war bereits nach …
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Evaluation of the photoprotective role of quercetin to selected light-adapted and shade-tolerant plant species
… aimed at evaluating the photoprotective role of quercetin to the selected plants, in addition to correlating how the production of flavonoids affects the plants photosynthesis. The photosynthetic rates of the selected plants were determined using LI-6400. The chlorophyll, carotenoid, anthocyanin, …
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Effects of Daily Oral Injections of Quercetin on Implanted Colon-25 Tumor Growth in Balb-C Mice
… oral dosages (0.4 mg, 0.8 mg, and 1.6 mg) of quercetin on Colon-25 tumors implanted in Balb-c mice were studied. The data in this study show that: (1) certain dosages of quercetin in alcohol solutions, reduces the weight, and size of implanted Colon-25 tumors in Balb-c mice, (2) these same …
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MCP-1, Macrophages and Tumorigenesis in the C3(1)/Sv40Tag Mouse Model of Breast Cancer: Benefits of Quercetin
… cell invasion, angiogenesis and metastasis. Quercetin is a flavonol present in several plant based foods with anti-inflammatory, anti-obesogenic and anti-carcinogenic actions; however, these effects of quercetin have not yet been explored in a mouse model of BrCa. The purpose of this study …
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Benefits of Quercetin on Metabolic and Inflammatory Biomarkers in High Fat Diet Induced Obesity: A Dose Response Study
… of many recent studies on diet-induced obesity. Quercetin, a polyphenolic compound found in many fruits and vegetables, is of interest due to its low toxicity and its wide range of bioactivity. While multiple studies have revealed the anti-inflammatory capabilities of quercetin in different mouse …
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The Influence of Quercetin, Curcumin, and Resistance Exercise On Anabolic Signaling In the Skeletal Muscle of Cachectic Mice
… wasting. Two naturally found nutraceuticals, quercetin and curcumin, as well as resistance exercise have all been shown to indirectly or directly influence molecular factors involved in increasing net protein synthesis. Thus the purpose of this study was to examine if quercetin or curcumin …
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Quercetin and chloroquine synergistically induces cell death in glioma cells via the increase of Ca2+ and ROS levels
… of malignant gliomas. We show herein that quercetin, a flavonoid, and chloroquine (CQ), an antimalarial drug, synergistically induce caspase-mediated apoptosis in T98G cells. Combined treatment with quercetin and CQ accumulated poly-ubiquitinated proteins and activated unfolded protein …
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Development of a novel 3-fluid nozzle for spray-dried microencapsulation of quercetin in zein and sodium caseinate
… the prolamin storage protein from corn, and quercetin, a polyphenolic flavonol compound with numerous health benefits, were chosen as a model system for this study. Zein nanoparticles ranging from 170 – 205 nm in size were successfully generated using a benchtop simulation of the proposed …
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The Effects of Carbohydrate and Quercetin on Team Sport Athletic Performance and Exercise-Induced Inflammation and Oxidative Stress
… activation of the enzyme xanthine oxidase (XO). Quercetin, a flavonol in plants that has shown some ergogenic effects with endurance exercise, inhibits XO in vitro. The effect of quercetin on team sport exercise had not been studied. We gave recreationally active males a commercial sports drink …
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Metabolism in Vascular Endothelial Cells: Effects of Hyperglycaemia, Pro-Inflammatory Cytokines and Polyphenols
… of exposure. Pre-treatment with the flavonol quercetin significantly reduced CAM expression in HUVECs. Next, the ability of quercetin to overcome the pro-inflammatory effects of hyperglycaemia and cytokine treatments in HUVECs was investigated using a metabolomics approach with a view to …
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The cardioprotective mechanisms of dietary flavonoids
… and cytotoxic effects of the dietary flavonoids quercetin, kaempferol, myricetin and two major quercetin metabolites, quercetin-3-glucoronide and 3’-O-methylquercetin, on fully differentiated H9c2 cells for the first time. The cardiomyocyte-like phenotype of the differentiated H9c2 cells was …
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Studies of the anti-cancer potential of flavonoids in Human Nasopharyngeal carcinoma cells
… property of two flavonoids namely luteolin and quercetin on nasopharyngeal carcinoma (NPC) using two NPC cell lines, HK1 and CNE2. We first identified the mechanisms leading to quercetin-mediated cell cycle arrest in NPC cells. Quercetin was able to inhibit E2F-1 transcriptional activity, thus …
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Comparison of dose-dependent outcomes in induction of cytogenotoxic responses by novel glucosyl flavonoids
The flavonoids quercetin, and its glucosides isoquercetin and rutin, are phytochemicals commonly consumed in plant-derived foods. They are associated with potential health-promoting effects such as anti-inflammation, anti-viral, anti-carcinogenesis, neuro- and cardio-protection, etc. Semi-synthetic …
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Using Esterase and Laccase Enzymes to Derivatize Bioactive Plant Phenolics for Altered Chemistry
… caffeic acid, ferulic acid, resveratrol, quercetin, morin, kaempferol and myricetin. Among the products formed by action on flavonols were dimers of quercetin, morin, and myricetin. Quercetin and myricetin dimers showed longer retention time on reversed phase chromatography. All three …
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