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University of Illinois at Urbana-Champaign

Cholinergic Regulation of the Mammalian Circadian System: Phase Shifting in Vivo and in Vitro in Wildtype and M(1) Knockout Mice Induced by Cholinergic Agonists

Abstract

dc:description

These experiments demonstrate that ACh regulates the circadian clock via at least two different pathways. One induces phase advances throughout the night and is mediated via the M1AChR. The other causes a biphasic, light-like response and is not mediated via the M1AChR.

Degree

thesis:*
Name thesis:degree_name
Ph.D.
Level thesis:degree_level
Dissertation
Discipline thesis:degree_discipline
Molecular and Integrative Physiology
Grantor
University of Illinois at Urbana-Champaign
Year dc:date
2015

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Buchanan, Gordon Frank
Contributors dc:contributor
  • Gillette, Martha U.

Subjects

dc:subject × 1

Rights

Language dc:language
eng

Identifiers

dc:identifier.*
Identifier
(MiAaPQ)AAI3086024
OAI identifier oai:identifier
oai:www.ideals.illinois.edu:2142/87226

Chain of custody

source
Harvested from
University of Illinois - Urbana-Champaign
Base URL
www.ideals.illinois.edu/oai-pmh
Last updated
2026-07-22
Source record
OAI-PMH GetRecord
citation

Buchanan, Gordon Frank. Cholinergic Regulation of the Mammalian Circadian System: Phase Shifting in Vivo and in Vitro in Wildtype and M(1) Knockout Mice Induced by Cholinergic Agonists. Dissertation thesis, University of Illinois at Urbana-Champaign, 2015. http://hdl.handle.net/2142/87226