Identification, Characterization and Mechanism of the Estrogen Regulation of the Gene Encoding the Sodium /Hydrogen Exchanger -Regulatory Factor (nhe-Rf)

"Finally, studies were designed to help define the physiological role of estrogen-induction of the NHE-RF gene using two model systems. Immunocytochemistry was used to visualize NHE-RF in MCF-7 cells. Secondly, we created adenovirus that express the wild type or anti-sense NHE-RF RNA. By infecting cells with the adenovirus we may overexpress or functionally ""knock out"" the NHE-RF protein and monitor the resulting effects on cell signaling, fluid exchange and cell cytoarchitecture."

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Microbiology

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2015

Author dc:creator

• Ediger, Tracy Rene

Contributors dc:contributor

• Katzenellenbogen, Benita S.

• Biology, Animal Physiology

Language dc:language

eng

Identifier

(MiAaPQ)AAI3070296

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/86642