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University of Illinois at Urbana-Champaign
A Mis-Expression Screen Identifies a PKA -Anchoring Protein in Antenna Lobe Development
Abstract
dc:descriptionOne of the genes recovered was the Drosophila A Kinase anchoring protein 200 (Akap200). This thesis discusses the further characterization of this gene. Akap200 is a Protein Kinase A (PKA) binding protein with multiple binding sites for other signaling molecules, including Protein Kinase C (PKC), Camodulin and F-actin. Further studies showed that ORN axons of the Akap200 mutants stall in the path to their targets. The loss of Akap200 has different effects on different classes of ORN axons. These findings provide new insights into the molecular mechanisms underlying ORN axon targeting.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Cell and Developmental Biology
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2015
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Zhang, Dongsheng
- Contributors dc:contributor
-
- Huey Hing
Subjects
dc:subject × 1Rights
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
- (MiAaPQ)AAI3337986
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/86319