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University of Illinois at Urbana-Champaign
Investigation of Phospholipid Bilayer Interactions With Substrates, Polymers, and Nanoparticles
Abstract
dc:descriptionThe last experiments described investigate the ability of water dispersed fullerene aggregates to interact with and disrupt cell membranes. Bilayers composed of both neat zwitterionic lipid headgroups and cationic lipid headgroups were examined to investigate charge interactions between the lipid headgroups and negatively charged fullerene aggregates. Our results indicate that water soluble fullerenes adhere to lipid headgroups and may disrupt cellular functions by either radical generation or cell membrane passivition.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Chemistry
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2015
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Spurlin, Tighe A.
- Contributors dc:contributor
-
- Gewirth, Andrew A.
Subjects
dc:subject × 1Rights
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
- (MiAaPQ)AAI3290388
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/84281