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University of Illinois at Urbana-Champaign
Immobilization of Catalytic DNA for Advanced Materials and Sensors
Abstract
dc:descriptionThe DNAzyme was also immobilized on patterned glass surfaces via covalent attachment. Substrate-functionalized 100 nm polystyrene particles were then hybridized in the absence and presence of Pb2+. The result was the Pb2+-mediated tethering of particles onto patterned grids, where Pb2+ induced the cleavage of the DNAzyme complex and prevented assembly of the particles. The assembly of these advanced materials was monitored in real-time using laser diffraction and was characterized via scanning electron microscopy. Addition of 10 muM Pb2+ showed >99% inhibition of assembly.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Chemistry
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2015
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Wernette, Daryl Paul
- Contributors dc:contributor
-
- Lu, Yi
Subjects
dc:subject × 1Rights
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
- (MiAaPQ)AAI3270048
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/84267