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University of Illinois at Urbana-Champaign

The Influence of Dietary Fat on The Cerebral Microvasculature: Compositional, Prostaglandin Synthetic, and Permeability Studies

Abstract

dc:description

In order to investigate the effects of long-term feeding of single fat sources, differing in essential fatty acids, on membrane-based phenomena in the cerebral cortex and microvasculature the following studies were conducted. Rats fed purified diets containing 10% corn, hydrogenated coconut, or linseed oils through two generations were sacrificed and the following items measured: fatty acyl composition of phospholipids, prostaglandin F(,2(alpha)) and prostacyclin synthesis by cortical slices and microvessels, respectively, kinetic parameters of adenosine uptake, and the potential involvement of eicosanoids in the uptake process.

Degree

thesis:*
Name thesis:degree_name
Ph.D.
Level thesis:degree_level
Dissertation
Discipline thesis:degree_discipline
Food Science
Grantor
University of Illinois at Urbana-Champaign
Year dc:date
2015

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Brown, Michael Lee

Subjects

dc:subject × 1

Rights

Language dc:language
eng

Identifiers

dc:identifier.*
Identifier
(UMI)AAI8409872
OAI identifier oai:identifier
oai:www.ideals.illinois.edu:2142/77445

Chain of custody

source
Harvested from
University of Illinois - Urbana-Champaign
Base URL
www.ideals.illinois.edu/oai-pmh
Last updated
2026-07-22
Source record
OAI-PMH GetRecord
citation

Brown, Michael Lee. The Influence of Dietary Fat on The Cerebral Microvasculature: Compositional, Prostaglandin Synthetic, and Permeability Studies. Dissertation thesis, University of Illinois at Urbana-Champaign, 2015. http://hdl.handle.net/2142/77445