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University of Illinois at Urbana-Champaign
Synthesis and Complexation Studies of Heterocyclic Compounds With Two or Three Contiguous Hydrogen Bonding Sites
Abstract
dc:descriptionThe design and synthesis of heterocyclic compounds with two or three adjacent hydrogen bonding sites is described. A general synthetic methodology was developed to produce 5-substituted anthyridine analogs. These compounds exhibited increased stability over the unsubstituted anthyridines. A novel hydrogen bond donor-donor-acceptor (DDA) unit was synthesized to mimic the hydrogen bond functionality of guanosine. A guanosine receptor was developed to ascertain the negative steric interactions inherent in Hamilton's guanosine receptor.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Chemistry
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2014
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Murray, Thomas James
- Contributors dc:contributor
-
- Zimmerman, Steven C.
Subjects
dc:subject × 1Identifiers
dc:identifier.*- Identifier
- (UMI)AAI9503280
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/72297