Synthesis and Complexation Studies of Heterocyclic Compounds With Two or Three Contiguous Hydrogen Bonding Sites
type: CreativeWork
description: The design and synthesis of heterocyclic compounds with two or three adjacent hydrogen bonding sites is described. A general synthetic methodology was developed to produce 5-substituted anthyridine analogs. These compounds exhibited increased stability over the unsubstituted anthyridines. A novel hydrogen bond donor-donor-acceptor (DDA) unit was synthesized to mimic the hydrogen bond functionality of guanosine. A guanosine receptor was developed to ascertain the negative steric interactions inherent in Hamilton's guanosine receptor.
abstract: The design and synthesis of heterocyclic compounds with two or three adjacent hydrogen bonding sites is described. A general synthetic methodology was developed to produce 5-substituted anthyridine analogs. These compounds exhibited increased stability over the unsubstituted anthyridines. A novel hydrogen bond donor-donor-acceptor (DDA) unit was synthesized to mimic the hydrogen bond functionality of guanosine. A guanosine receptor was developed to ascertain the negative steric interactions inherent in Hamilton's guanosine receptor.
author: Murray, Thomas James
keywords: Chemistry, Organic
date published: 2014-12-17T21:29:15Z
date modified: 2026-07-22T22:26:06Z
provider: University of Illinois - Urbana-Champaign
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: University of Illinois at Urbana-Champaign

PropertyValue
property ID: Handle
value: http://hdl.handle.net/2142/72297