The potential role of interleukin-2 in impaired cell-mediated immunity of iron deficiency

Iron deficiency impairs cell-mediated immunity, which is primarily dependent on T-lymphocyte functions including production of the cytokine, interleukin 2 (IL-2). The potential role of IL-2 production and responsiveness in impaired cell-mediated immunity of iron deficiency was investigated in a series of experiments. Immune parameters were measured in unstimulated and concanavalin A (Con A)-stimulated spleen lymphocytes from rats and mice. Dietary iron deficiency induced in the weanling Sprague-Dawley rat and C57/B16 mouse were used as the nutritional models.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Nutritional Sciences

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2011

Author dc:creator

• Helyar, Lesley

• Biology, Cell
• Biology, Microbiology
• Health Sciences, Nutrition

Statement dc:rights

• Copyright 1991 Helyar, Lesley

Language dc:language

eng

Identifier

AAI9210834
(UMI)AAI9210834

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/20250