Cholesterol Lowering Effects of Milk with Added Phytosterols

<h1> </h1> <p>Foods incorporating plant sterols (PS) reduce Low-density lipoprotein (LDL) on average approximately 10%. PS with a higher lipid solubility may promote greater reductions. We examined the cholesterol lowering effect of a novel triglyceride recrystallized phystosterol (TRP). Twenty subjects (mean ± SD; age, 56 ± 10 years; BMI, 27 ± 5) with elevated LDL (>100 mg/dL) participated in three 4-week phases; Phase I, 2% milk; Phase II, milk with 2.0 grams (g) free PS; Phase III, milk with 2.0 g TRP. Before and after each phase two fasting blood draws were obtained for determination of serum cholesterol. Between the 2% and TRP milk phases total, LDL and High-density lipoprotein (HDL) cholesterol changed by -9.0% (p = .001), -11.0% (p = .002) and -8.0% (p = .029) respectively: between the free PS and TRP milk phases total, LDL and HDL cholesterol changed by -3.3% (p = .136), -2.3% (p = 1.00), -6.4% (p = .023) respectively. Apo B concentrations resulted in a decrease of -6.9% (p = .048) between the free PS and TRP milk phases and did not significantly change between the 2% and TRP milk phases. Triglycerides and Apo A1 concentrations did not significantly change between any of the phases. In conclusion, TRP can be effectively incorporated into a skim milk resulting in a significant cholesterol lowering effect. (218 words)</p>

Name thesis:degree_name

Master of Science

Discipline thesis:degree_discipline

Kinesiology

Year dc:date.available

2012

Author dc:creator

• Cusack, Laura Kells

Contributors dc:contributor

• C.M. Maresh; W.J. Kraemer
• J.S. Volek

• cholesterol
• phytosterol
• plant sterol
• plant stanol
• apolipoprotein B
• apolipoprotein A1
• LDL
• HDL

Repository record dc:identifier

https://digitalcommons.lib.uconn.edu/gs_theses/270

OAI identifier oai:identifier

oai:digitalcommons.lib.uconn.edu:gs_theses-1294