Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 14399 for “"HDL"”.
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Graphics Processors for an HDL Simulator
A new CAD tool, aimed at providing a simple graphical interface to the chip-level simulation system GSP, has been developed. It consists of pre and post-processors allowing the user to model systems using pre-defined library as well as custom modules and to view their outputs in a more familiar …
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Very low HDL cholesterol: The GSH Experience
Background In epidemiological studies low HDL-C is associated with increased cardiovascular risk. In exceptional cases, e.g., patients with Apo A1 Milano, low levels of HDL-C are cardioprotective. Very little is known about the characteristics of South African patients with very low HDL-C. A …
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HDL implementation of a controller area network node
<p>With increasing technology inside automobiles, especially law enforcement vehicles, there is a growing need for centralized wiring and device interconnection methods. Each new technology, such as GPS navigation units and in-vehicle video systems, includes a corresponding wiring harness that …
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Application of object-orientation to HDL-based designs
… based on Hardware Description Languages (HDL). This methodology has helped to master the possibilities inherent in our ability to manufacture ever-larger designs. However. while HDL based design methodology is sufficient to address today's standard ASIC sizes, it reaches its limits when …
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HDL Phospholipid and ABCA1-Mediated Cholesterol Efflux Are Reduced in Patients with Very High HDL-C Who Develop Early Coronary Artery Disease
… levels of high-density lipoprotein cholesterol (HDL-C) are strongly inversely associated with coronary artery disease (CAD), and high HDL-C is generally associated with apparent ‘protection’ from CAD. OBJECTIVE: We identified a number of individuals with high HDL-C levels who develop CAD, a …
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Molecular Basis of HDL-Mediated Endothelial Cell Migration and Reendothelialization
… circulating levels of high density lipoprotein (HDL) cholesterol. The atheroprotective nature of HDL is attributed mainly to its role in reverse cholesterol transport (RCT). However, recent reports of human and animal studies have suggested that the atheroprotective nature of HDL is not …
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Structure and function studies on five homogeneous reconstituted HDL complexes
High density lipoprotein (HDL) is believed to be involved in reverse cholesterol transport. HDL consists primarily of phospholipids, cholesterol, cholesterol esters, and apolipoprotein A-I (apo A-I). However, HDL is extremely heterogeneous in size composition and the structure of its lipoprotein …
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Study of anti-inflammatory functions of HDL in experimental mouse models
HDL has important immunomodulatory properties, including the attenuation of lipopolysaccharide (LPS)-induced inflammatory response. Τhe purpose of this study was to investigate the potential correlation between HDL shape and composition and its anti-inflammatory functions and properties in …
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Effects of phosphatidylinositol on ApoA-I metabolism: Implications in HDL metabolism
… made to develop therapeutics that raise plasma HDL levels to aid in the prevention of CHD. HDL levels are believed to be inversely associated with the risk of developing CHD. Naturally occurring phospholipids such as phosphatidylinositol (PI), have been shown to increase plasma apoA-I levels and …
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The Role of Lipid-Free Apolipoprotein A-I and PCPE2 in HDL Metabolism
… enhancer 2 (PCPE2) in high density lipoprotein (HDL) metabolism. ApoA-I comprises ~70 percent of the protein within HDL and has an essential role in cholesterol efflux from peripheral cells as part of the reverse cholesterol transport pathway. Lipid-free apoA-I undergoes conformational changes as …
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Mining Genomic Variants And Causal Pathways Linking Hdl And Triglycerides To Coronary Disease
… that high-density lipoprotein cholesterol (HDL-C) may protect from disease while high triglycerides (TGs) increase CHD risk. However, the causality of HDL-C and TG to CHD remains controversial. New genetic methodologies have allowed a better look into causal pathways underlying relationships …
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Evaluating Simulink HDL coder as a framework for flexible and modular hardware description
… the performance and viability of Simulink and HDL Coder from MathWorks as an alternative workflow for producing hardware description. Several designs were implemented towards this end. An FFT-based signal analyzer served as a pathfinding application to better understand the tools. In order to …
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3D Simulation of the Velodyne HDL-32E Lidar Integrated with an Autonomous Marine Vehicle
… is programmed for modeling the Velodyne HDL-32E LIDAR used on the WAM-V vehicle in the marine environment for obstacle detection. The model takes into account sensor integration, sensor error, and error correction. Theoretical analysis includes consideration of atmospheric refraction, …
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Partitioning of large HDL ASIC designs into multiple FPGA devices for prototyping and verification
The ASIC (Application specific Integrated Circuit) designs grow continuously bigger and bigger. This causes dramatic increase in the simulation run time. It is very hard to simulate these designs because the simulation time has risen from hours to days and weeks. Hardware Embedded Simulation (HES) …
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Investigating high-density lipoprotein (HDL) subfractions, composition and functionality in people living with HIV
… and functionality of high-density lipoprotein (HDL) subfractions are altered in the presence of cardiovascular risk factors. We aimed to explore whether HIV and/or ART modulate HDL subfractions and functionality in a population of people living with HIV (PLWH). Methods: Fifty healthy …
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Using chemical biology as a tool to probe the mechanism of the HDL receptor
The high density lipoprotein (HDL) receptor, scavenger receptor, class B, type I (SR-BI), is a cell surface glycoprotein that controls HDL structure and metabolism by mediating cellular selective uptake of lipids from HDL. The mechanism underlying SR-BI-mediated lipid transfer involves a two-step …
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RARE ABCA1 VARIANTS FOUND ONLY IN AFRICAN AMERICANS AND HOW THEY AFFECT LIPID EFFLUX AND NASCENT HDL FORMATION
… due to almost non-existent levels of HDL-C and increased atherosclerosis in these subjects. The idea that HDL-C and atherosclerosis are inversely correlated provides evidence for the benefit of these anti-atherogenic particles. However, African Americans generally have higher HDL-C, …
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HDL-C As Most Predictive Variable of Visceral Adipose Tissue in Young Military Personnel of the National Guard
… in both sexes. Statistical analyses identify HDL cholesterol (HDL-C) and waist circumference as significant predictive variables of VAT, after adjusting for age and sex. Follow-up data from two participants was collected but excluded from statistical analysis due to small sample size. …
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Understanding the relationship between high-density lipoprotein (HDL) subclass distribution and functionality in patients at risk of cardiovascular disease
… and hypertension. High-density lipoprotein (HDL) has traditionally served as a marker for CVD risk. Latest studies, however, propose that the composition and subclass distribution and the anti-atherogenic function of HDL are more accurate predictors of CVD risk. We therefore explored whether …
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