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University of Tennessee Health Science Center
Interplay of Antibody Responses to Closely Related Viruses and Autoimmunity
Abstract
dc:description.abstract<p>Antibodies produced by B cells are crucial for eliminating infectious pathogens and preventing secondary infection. However, antibodies may also bind to self-antigens and contribute to autoimmune disease. While pathogen infections have been associated with development of autoimmune diseases, the precise contributions of viral infections to autoimmunity remain elusive. The presence of autoreactive antibodies is associated with an increased risk of developing autoimmune disease. Thus, analyzing the impact of viral infection and vaccination on the development of autoreactive antibodies will provide essential insight into mechanisms that contribute to autoimmune disease.</p>
Degree
thesis:*- Name thesis:degree_name
- Doctor of Philosophy (PhD)
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Biomedical Sciences
- Year dc:date.available
- 2024
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Lin, Chun-Yang
- Contributors dc:contributor
-
- Maureen McGargill, PhD
Subjects
dc:subject × 11Identifiers
dc:identifier.*- Repository record dc:identifier
- https://dc.uthsc.edu/dissertations/686
- OAI identifier oai:identifier
- oai:dc.uthsc.edu:dissertations-1686