CHARACTERIZATION OF THE FUNCTION OF THE DEAD-BOX RNA HELICASE DBP2

In eukaryotes, there are highly coupled mechanisms that require RNA-binding proteins to facilitate gene expression. Proper RNA structure and ribonucleoprotein (RNP) complex formation are critical for gene expression. DEAD-box proteins are the largest class of RNA helicases that play fundamental roles in RNA and RNP structure remodeling. However, the precise biological role of the vast majority of the ~ 40 members in this family has not been completely described. Therefore, my research focused on characterizing the role of the DEAD-box RNA helicase Dbp2 during gene expression in S. cerevisiae.

Name thesis:degree_name

Doctor of Philosophy (PhD)

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Biochemistry

Year

2015

Author dc:creator

• Ma, Wai Kit

Contributors dc:contributor

• Elizabeth J Tran
• Barbara L Golden
• Mark C Hall
• Robert L Geahlen

• Chromatin
• Dbp2
• DEAD-box
• Helicase
• RNA
• RNA-Protein complex

Repository record dc:identifier

https://docs.lib.purdue.edu/open_access_dissertations/1127

OAI identifier oai:identifier

oai:docs.lib.purdue.edu:open_access_dissertations-2343