Regulation of the Tubulin Homolog FtsZ in <i>Escherichia coli</i>

<p><em>Escherichia coli</em> is a well-known pathogen, and importantly, a widely used model organism in all fields of biological sciences for cloning, protein purification, and as a model for Gram-negative bacterial species. And yet, researchers do not fully understand how this bacterium replicates and divides. Every year additional division proteins are discovered, which adds complexity to how we understand <em>E. coli</em> undergoes cell division. Due to their specific roles in cytokinesis, some of these proteins may be potential targets for development of antibacterials or bacteriostatics, which are much needed for fighting the current global antibacterial deficit. My thesis work focuses on understanding how <em>E. coli</em> cell division is regulated.</p>

Name thesis:degree_name

Doctor of Philosophy

Level thesis:degree_level

Doctoral

Discipline thesis:degree_discipline

Biology

Grantor

The Graduate School and University Center of The City University of New York

Year dc:date.available

2018

Author dc:creator

• Buczek, Monika S

Advisor dc:contributor.advisor

• Anuradha Janakiraman

Committee members dc:contributor.committeemember

• David Jeruzalmi
• Shireen Saleque
• Andrew Darwin
• Lars Dietrich
• Anuradha Janakiraman

• Bacteriology
• Biochemistry
• Biology
• Biophysics
• Cell Biology
• Cellular and Molecular Physiology
• Genetics
• Microbial Physiology
• Molecular Biology
• Molecular Genetics
• Organismal Biological Physiology
• Structural Biology
• cytokinesis
• division
• FtsZ
• E. coli
• microbiology

Repository record dc:identifier

https://academicworks.cuny.edu/gc_etds/2738

OAI identifier oai:identifier

oai:academicworks.cuny.edu:gc_etds-3774