Escherichia coli is a well-known pathogen, and importantly, a widely used model organism in all fields of biological sciences for cloning, protein purification, and as a model for Gram-negative bacterial species. And yet, researchers do not fully understand how this bacterium replicates and divides. Every year additional division proteins are discovered, which adds complexity to how we understand E. coli undergoes cell division. Due to their specific roles in cytokinesis, some of these proteins may be potential targets for development of antibacterials or bacteriostatics, which are much needed for fighting the current global antibacterial deficit. My thesis work focuses on understanding how E. coli cell division is regulated.
","abstract_html":"<p><em>Escherichia coli</em> is a well-known pathogen, and importantly, a widely used model organism in all fields of biological sciences for cloning, protein purification, and as a model for Gram-negative bacterial species. And yet, researchers do not fully understand how this bacterium replicates and divides. Every year additional division proteins are discovered, which adds complexity to how we understand <em>E. coli</em> undergoes cell division. Due to their specific roles in cytokinesis, some of these proteins may be potential targets for development of antibacterials or bacteriostatics, which are much needed for fighting the current global antibacterial deficit. My thesis work focuses on understanding how <em>E. coli</em> cell division is regulated.</p>","abstract_has_math":false,"creators":["Buczek, Monika S"],"institution":"The Graduate School and University Center of The City University of New York","degree_name":"Doctor of Philosophy","degree_level":"Doctoral","degree_discipline":"Biology","degree_department":null,"school":null,"contributors":[],"advisors":["Anuradha Janakiraman"],"committee_chairs":[],"committee_members":["David Jeruzalmi","Shireen Saleque","Andrew Darwin","Lars Dietrich","Anuradha Janakiraman"],"year":2018,"date_issued":"2018-05-01T07:00:00Z","date_published":"2018-05-01T07:00:00Z","updated_at":"2026-07-24T01:59:38Z","subjects":["Bacteriology","Biochemistry","Biology","Biophysics","Cell Biology","Cellular and Molecular Physiology","Genetics","Microbial Physiology","Molecular Biology","Molecular Genetics","Organismal Biological Physiology","Structural Biology","cytokinesis","division","FtsZ","E. coli","microbiology"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://academicworks.cuny.edu/gc_etds/2738","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Anuradha Janakiraman"]},{"key":"dc:contributor.committeemember","label":"Committee Member","values":["David Jeruzalmi","Shireen Saleque","Andrew Darwin","Lars Dietrich","Anuradha Janakiraman"]},{"key":"dc:creator","label":"Author","values":["Buczek, Monika S"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.available","label":"Dc Date Available","values":["2020-05-30T07:00:00Z"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Biology"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Doctoral"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Doctor of Philosophy"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["The Graduate School and University Center of The City University of New York"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Bacteriology","Biochemistry","Biology","Biophysics","Cell Biology","Cellular and Molecular Physiology","Genetics","Microbial Physiology","Molecular Biology","Molecular Genetics","Organismal Biological Physiology","Structural Biology","cytokinesis","division","FtsZ","E. coli","microbiology"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://academicworks.cuny.edu/gc_etds/2738"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Escherichia coli is a well-known pathogen, and importantly, a widely used model organism in all fields of biological sciences for cloning, protein purification, and as a model for Gram-negative bacterial species. And yet, researchers do not fully understand how this bacterium replicates and divides. Every year additional division proteins are discovered, which adds complexity to how we understand E. coli undergoes cell division. Due to their specific roles in cytokinesis, some of these proteins may be potential targets for development of antibacterials or bacteriostatics, which are much needed for fighting the current global antibacterial deficit. My thesis work focuses on understanding how E. coli cell division is regulated.
"]},{"key":"dc:title","label":"Title","values":["Regulation of the Tubulin Homolog FtsZ in Escherichia coli"]}]}],"canonical_facts":{"dc:contributor.advisor":["Anuradha Janakiraman"],"dc:contributor.committeemember":["David Jeruzalmi","Shireen Saleque","Andrew Darwin","Lars Dietrich","Anuradha Janakiraman"],"dc:creator":["Buczek, Monika S"],"dc:date.available":["2020-05-30T07:00:00Z"],"dc:description.abstract":["Escherichia coli is a well-known pathogen, and importantly, a widely used model organism in all fields of biological sciences for cloning, protein purification, and as a model for Gram-negative bacterial species. And yet, researchers do not fully understand how this bacterium replicates and divides. Every year additional division proteins are discovered, which adds complexity to how we understand E. coli undergoes cell division. Due to their specific roles in cytokinesis, some of these proteins may be potential targets for development of antibacterials or bacteriostatics, which are much needed for fighting the current global antibacterial deficit. My thesis work focuses on understanding how E. coli cell division is regulated.
"],"dc:identifier":["https://academicworks.cuny.edu/gc_etds/2738"],"dc:subject":["Bacteriology","Biochemistry","Biology","Biophysics","Cell Biology","Cellular and Molecular Physiology","Genetics","Microbial Physiology","Molecular Biology","Molecular Genetics","Organismal Biological Physiology","Structural Biology","cytokinesis","division","FtsZ","E. coli","microbiology"],"dc:title":["Regulation of the Tubulin Homolog FtsZ in Escherichia coli"],"thesis:degree_discipline":["Biology"],"thesis:degree_level":["Doctoral"],"thesis:degree_name":["Doctor of Philosophy"],"thesis:institution_name":["The Graduate School and University Center of The City University of New York"]},"updated_at":"2026-07-24T01:59:38Z"}