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Showing 1 to 20 of 60 for “"NSAID"”.
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Structural and thermal characterisation of NSAIDs and cyclodextrin-NSAID complexes
Non-steroidal anti-inflammatory drugs (NSAIDs) are used for the prevention of pain and inflammation. These symptoms are brought about by the action of biochemicals such as prostoglandins, which result from the conversion of a fatty acid, known as arachidonic acid, by the enzyme cyclooxygenase (COX) …
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Regulation of Cataractogenesis in Culture Bovine Lenses by 5-Phenyldithiole-3-Thione-NSAID Hybrid Molecules
… (H2S) and Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen can mitigate cataractogenesis. Therefore, this study investigated the pharmacological actions and mechanisms by which ATB 343 (indomethacin & H2S donor) and ATB 337 (diclofenac & H2S donor) regulate time-dependent and …
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Advanced engineering of Fibrous Non-steroidal anti-inflammatory drug (NSAID) films for buccal application using Electrohydrodynamic Atomisation
… excipients. EHDA was employed to engineer NSAID drugs in fibre film form for buccal delivery. EHDA was selected to develop fibre film of Indomethacin, Diclofenac Sodium, Ketoprofen, and Piroxicam in cooperation of PVP, Ethocel, Methocel, HPMC, and Tween 80. Morphology of electrospun films …
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Concomitant Suppression Of Both Cox-1 And Cox-2 Is Not Sufficient To Cause Gastroenteropathy Associated With Chronic Nsaid Use
Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most widely used nonaddictive medications for the management of chronic pain and inflammation; however, these drugs are associated with many gastrointestinal and cardiovascular adverse events, including intestinal bleeding, ulceration, stenosis, …
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Monitoring medication problems in the elderly and strategies for their reduction.
… nonsteroidal anti-inflammatory drugs (NSAIDs) were responsible in a quarter (24.5%, 14/57). The incidence of MRPs estimated against frequency of prescribing of each medication group was also highest with NSAIDs (17.6%, 18/102). Among groups of medication associated with MRPs, the …
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The nature, extent, and range of evidence of the premature constriction or closure of the ductus arteriosus in utero unrelated to known non-steroidal-anti-inflammatory drug exposure: a scoping review
… lungs. Non-steroidal anti-inflammatory drug (NSAID) use in late pregnancy can cause premature constriction or closure of the ductus arteriosus (PCDA), though cases also occur without NSAID exposure. Understanding non-NSAID-related PCDA (NNPCDA) is important for prenatal care. Objective: To …
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Epigallocatechin-3-gallate and tolfenamic acid induces apoptosis and growth inhibition in head and neck cancer : Involvement of NSAID activated gene-1
… and nonsteroidal anti-inflammatory drugs (NSAIDs) as chemopreventive agents. At present, the chemopreventive agents that have been most widely investigated as chemopreventive agents are NSAIDs and anti-oxidants.Epigallocatechin-3-gallate (EGCG), a major polyphenolic constituent of green …
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Alterações morfológicas promovidas pelo uso de anti-inflamatórios não-esteroidais.
… of drugs. The nonsteroidal anti - inflammatory (NSAID) therapeutic class occupies frequently the ranking of more utilized drugs in the automedication practice , and it do n o t put out of order when speak s about t he adverse reactions’ development during its inadequate (or adequate) use. With …
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The role of a pharmacist in screening, communicating and reporting the risks of cardiovascular disease associated with non-steroidal anti-inflammatory drugs and the perception of the population
… non-steroidal anti-inflammatory drugs (NSAIDs), pose significant challenges to effective prevention and self-management strategies. This thesis adopts a mixed-methods approach to examine three interrelated dimensions of this issue: public knowledge of NSAID-related CVD risks, …
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Identification of bacteria-regulated mechanisms for the pathogenesis of inflammatory bowel diseases (IBD) and development of upconverting nanoparticle (UCNP) luminescence imaging for the monitoring of gut bacteria
… disease. Non-steroidal anti-inflammatory drugs (NSAIDs) are believed to exacerbate inflammation in patients with IBD. However, the literature demonstrates no consensus on the association between NSAID use and IBD, with some studies reporting that only high dose NSAID treatment are more likely for …
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The renal effects of nonsteroidal anti-inflammatory drugs (NSAIDS) in dogs with chronic kidney disease (CKD)
… Nonsteroidal anti-inflammatory drugs (NSAIDs) produce both their beneficial and detrimental effects through inhibition of the cyclooxygenase enzyme and subsequent interference with prostaglandin production. Healthy canine kidneys express both COX-1 and COX-2, although basal COX-2 …
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Role of Endogenous Prostaglandins on Kainic Acid Induced Seizure Activity
It is not well clarified whether NSAID including COX-2 inhibitors aggravates the epileptic seizure. Pretreatments with NSAID(nonsteroidal anti-inflammatory drug) including COX-2 inhibitors such as indomethacin, nimesulide and celecoxib is known to aggravate the kainic acid(KA)-induced seizure …
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Quantifying the Risk of Beta-Blockers and Non-Steroidal Anti-Inflammatory Drugs in Asthma
… and non-steroidal anti-inflammatory drugs (NSAIDs) are often avoided in asthma over risk of bronchospasm which may vary according to drug selectivity and duration of administration. This thesis attempts to quantify the risk of beta-blocker and NSAID exposure in asthma by synthesising …
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Dairy Product Intake and Racial Differences In Prostate Cancer Aggressiveness
… cancer aggressiveness and grade was modified by NSAID use (p for interaction = 0.01 for both aggressiveness and grade). The association between calcium and aggressiveness and grade differed by race, but this difference was not statistically significant. These results do not suggest that dairy …
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Factors influencing development and outcome of equine gastrointestinal disease
… and non-steroidal anti-inflammatory drug (NSAID) administration, putting them at high risk for formation of both squamous (ESGD) and glandular (EGGD) gastric ulcers. Prophylactic anti-ulcer medication selection is complicated by differences in etiology and response to treatment of these two …
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A Clinical Characteristics of Adverse Drug Reaction in Pediatrics
… (7 patients, 7%), Macrolides (3 patients, 3%), NSAID (13 patients, 13%), Acetaminophen (8 patients, 8%), Phenytoin (12 patients, 12%), Anti-cancer medicine (4 patients, 4%), Sedative (1 patient, 1%) and Antiflammatory (1 patient, 1%). For 16 patients among them, drug challenge test was …
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Effects of chronic exposure to ibuprofen and naproxen on Florida flagfish (Jordanella floridae) over one complete life-cycle
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a class of drugs prescribed to relieve pain, fever and inflammation, and are among the most commonly consumed medications in Ontario. Approximately 70% of the ingested dose is excreted unchanged or as an active metabolite, much of which reaches the …
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An assessment of drug related problems in the elderly in the community and methodology for their prevention.
… related. Non-steroidal anti-inflammatory drugs (NSAIDs) were the main drug group involved, being responsible for 15/54 (28%) of admissions primarily due to a DRP. Over 66% of admissions due to adverse effects of NSAIDs were considered to be ‘definitely preventable’, and a further 27% ‘possibly …
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