The effectiveness of prophylactic etodolac on post-endodontic pain

The purpose of this study was to determine if prophylactic oral administration of etodolac would significantly reduce post-endodontic pain, when compared to ibuprofen and a placebo.;Thirty-six patients requiring conventional root canal therapy consented to single blind oral administration of either 400 mg of etodolac, 600 mg of ibuprofen, or a placebo, prior to conventional root canal therapy. Pain evaluation was completed on a pain survey that consisted of visual analog scales at the following time intervals; initial, immediately after, 4 hours, 8 hours, 12 hours, 24 hours, 48 hours, and 72 hours after initiation of root canal therapy.;A significant difference was found for ibuprofen's ability to reduce post-endodontic pain at 4 and 8 hours after initiation of root canal therapy, when compared to etodolac and a placebo (4 Hours P-value = 0.0111; 8 Hours P-value = 0.0397). A significant difference was also found for the periapical diagnosis and the need for additional medication after completion of root canal therapy (P-value = 0.0077).

Name thesis:degree_name

MS

Level thesis:degree_level

Thesis

Discipline thesis:degree_discipline

Not Listed

Year dc:date.available

1999

Author dc:creator

• Menke, Eric Richard

Contributors dc:contributor

• C. Russell Jackson.

• Dentistry
• Pharmacology

Identifier

https://researchrepository.wvu.edu/etd/1060

OAI identifier oai:identifier

oai:researchrepository.wvu.edu:etd-2063