{"id":{"repo_id":"wvu","oai_identifier":"oai:researchrepository.wvu.edu:etd-2063"},"canonical_url":"https://search.dev.ndltd.org/etd/wvu/oai:researchrepository.wvu.edu:etd-2063","repository":{"repo_id":"wvu","name":"West Virginia University","base_url":"https://researchrepository.wvu.edu/do/oai/"},"display":{"title":"The effectiveness of prophylactic etodolac on post-endodontic pain","abstract":"The purpose of this study was to determine if prophylactic oral administration of etodolac would significantly reduce post-endodontic pain, when compared to ibuprofen and a placebo.;Thirty-six patients requiring conventional root canal therapy consented to single blind oral administration of either 400 mg of etodolac, 600 mg of ibuprofen, or a placebo, prior to conventional root canal therapy. Pain evaluation was completed on a pain survey that consisted of visual analog scales at the following time intervals; initial, immediately after, 4 hours, 8 hours, 12 hours, 24 hours, 48 hours, and 72 hours after initiation of root canal therapy.;A significant difference was found for ibuprofen's ability to reduce post-endodontic pain at 4 and 8 hours after initiation of root canal therapy, when compared to etodolac and a placebo (4 Hours P-value = 0.0111; 8 Hours P-value = 0.0397). A significant difference was also found for the periapical diagnosis and the need for additional medication after completion of root canal therapy (P-value = 0.0077).","abstract_html":"The purpose of this study was to determine if prophylactic oral administration of etodolac would significantly reduce post-endodontic pain, when compared to ibuprofen and a placebo.;Thirty-six patients requiring conventional root canal therapy consented to single blind oral administration of either 400 mg of etodolac, 600 mg of ibuprofen, or a placebo, prior to conventional root canal therapy. Pain evaluation was completed on a pain survey that consisted of visual analog scales at the following time intervals; initial, immediately after, 4 hours, 8 hours, 12 hours, 24 hours, 48 hours, and 72 hours after initiation of root canal therapy.;A significant difference was found for ibuprofen's ability to reduce post-endodontic pain at 4 and 8 hours after initiation of root canal therapy, when compared to etodolac and a placebo (4 Hours P-value = 0.0111; 8 Hours P-value = 0.0397). A significant difference was also found for the periapical diagnosis and the need for additional medication after completion of root canal therapy (P-value = 0.0077).","abstract_has_math":false,"creators":["Menke, Eric Richard"],"institution":null,"degree_name":"MS","degree_level":"Thesis","degree_discipline":"Not Listed","degree_department":null,"school":null,"contributors":["C. Russell Jackson."],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1999,"date_issued":"1999-05-01T07:00:00Z","date_published":"1999-05-01T07:00:00Z","updated_at":"2026-07-24T06:15:16Z","subjects":["Dentistry","Pharmacology"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["https://researchrepository.wvu.edu/etd/1060"],"render_values":[{"text":"https://researchrepository.wvu.edu/etd/1060","href":"https://researchrepository.wvu.edu/etd/1060","code":true}]}]},"links":{"outbound_url":"https://doi.org/10.33915/etd.1060","outbound_label":"DOI","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["C. 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Pain evaluation was completed on a pain survey that consisted of visual analog scales at the following time intervals; initial, immediately after, 4 hours, 8 hours, 12 hours, 24 hours, 48 hours, and 72 hours after initiation of root canal therapy.;A significant difference was found for ibuprofen's ability to reduce post-endodontic pain at 4 and 8 hours after initiation of root canal therapy, when compared to etodolac and a placebo (4 Hours P-value = 0.0111; 8 Hours P-value = 0.0397). A significant difference was also found for the periapical diagnosis and the need for additional medication after completion of root canal therapy (P-value = 0.0077)."]},{"key":"dc:title","label":"Title","values":["The effectiveness of prophylactic etodolac on post-endodontic pain"]}]}],"canonical_facts":{"dc:contributor":["C. Russell Jackson."],"dc:creator":["Menke, Eric Richard"],"dc:date.available":["2019-01-17T08:00:00Z"],"dc:description.abstract":["The purpose of this study was to determine if prophylactic oral administration of etodolac would significantly reduce post-endodontic pain, when compared to ibuprofen and a placebo.;Thirty-six patients requiring conventional root canal therapy consented to single blind oral administration of either 400 mg of etodolac, 600 mg of ibuprofen, or a placebo, prior to conventional root canal therapy. Pain evaluation was completed on a pain survey that consisted of visual analog scales at the following time intervals; initial, immediately after, 4 hours, 8 hours, 12 hours, 24 hours, 48 hours, and 72 hours after initiation of root canal therapy.;A significant difference was found for ibuprofen's ability to reduce post-endodontic pain at 4 and 8 hours after initiation of root canal therapy, when compared to etodolac and a placebo (4 Hours P-value = 0.0111; 8 Hours P-value = 0.0397). A significant difference was also found for the periapical diagnosis and the need for additional medication after completion of root canal therapy (P-value = 0.0077)."],"dc:identifier":["https://doi.org/10.33915/etd.1060","https://researchrepository.wvu.edu/etd/1060"],"dc:subject":["Dentistry","Pharmacology"],"dc:title":["The effectiveness of prophylactic etodolac on post-endodontic pain"],"thesis:degree_discipline":["Not Listed"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["MS"]},"updated_at":"2026-07-24T06:15:16Z"}