Back to results
Wake Forest University
AMP-ACTIVATED PROTEIN KINASE AND ITS ROLE IN THERAPEUTIC RESPONSE IN ACUTE MYELOID LEUKEMIA
Abstract
dc:description.abstractAcute myeloid leukemia (AML) is an aggressive cancer of the bone marrow characterized by poor prognosis and resistance to chemotherapy. The way in which cancerous cells are able to metabolically adapt to various physiological and metabolic stressors allows them to thrive and proliferate. A leading candidate to coordinate this oxidative metabolic shift is the AMP-activated protein kinase (AMPK).
Degree
thesis:*- Grantor dc:publisher
- Wake Forest University
- Year dc:date.issued
- 2018
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Ghiraldeli, Lais Pereira
Subjects
dc:subject × 1Rights
- Language dc:language.iso
- en
Identifiers
dc:identifier.*- Handle dc:identifier.uri
- http://hdl.handle.net/10339/92387
- OAI identifier oai:identifier
- oai:wakespace.lib.wfu.edu:10339/92387