Development of a comprehensive annotation and curation framework for analysis of Glossina Morsitans Morsitans expresses sequence tags

This study has successfully identified transcripts differentially expressed in the salivary gland and midgut and provides candidate genes that are critical to response to parasite invasion. Furthermore, an open-source Glossina resource (G-ESTMAP) was developed that provides interactive features and browsing of functional genomics data for researchers working in the field of Trypanosomiasis on the African continent.

Grantor dc:publisher.institution

University of the Western Cape

Year dc:date.issued

2011

Author dc:creator

• Wamalwa, Mark

Advisor dc:contributor.advisor

• Christoffels, Alan

• Transcriptome annotation system
• Comparative transcriptomics
• Annotation pipeline
• Database
• Manual curation
• OrthoMCL
• Glossina morsitans morsitans
• Expressed sequence tags
• Open reading frames