Myers-Inspired Selenium-Mediated Isomerization: An Efficient Generation of Contra-Thermodynamic Allenes and Alkenes with the Potential for Reductive Deamination of Primary Amines and Metal-Free Hydrogenation of Dienes

Novel methods of catalytic metal-free isomerization reactions are scarce. By combining precedents in reductive defunctionalization reactions, coupled with previous advances in selenium-catalyzed C-N bond forming reactions, we have developed a contemporary but efficient manner of reaching contra-thermodynamic isomers of alkenes and alkynes. These isomerizations follow a well envisioned mechanistic path that may lead to further development in reductive deamination reactions, such as the reduction of primary amines such as anilines, and diamines to monoenes.

Author dc:creator

• Landing, Samuel Dane

Advisor dc:contributor.advisor

• Michael, Forrest E

• contra-thermodynamic
• isomerization
• meyers'
• olefin
• selenium
• Organic chemistry

Statement dc:rights

• none

Language dc:language.iso

en_US

Handle dc:identifier.uri

http://hdl.handle.net/1773/50734

OAI identifier oai:identifier

oai:digital.lib.washington.edu:1773/50734