Brain anatomy: investigations of the effects of aging, fitness, and arterial stiffness

This work explores the mechanisms and lifestyle modifiers of brain anatomy throughout the aging process. First, a thorough review of the mechanisms of fitness on brain anatomy is presented. Next, a study examining the effects of aging and fitness on cortical and subcortical brain anatomy in a group of older adults (55-87 years old) is presented. We examine the degree to which cortical, subcortical, and global volumes are sensitive to both age and fitness. Lastly, the effect of cerebrovascular stiffness on the anatomical difference between and within individual subjects is explored across the lifespan (18-75 years old).

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Neuroscience

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2017

Author dc:creator

• Fletcher, Mark Allen

Contributors dc:contributor

• Fabiani, Monica
• Gratton, Gabriele
• Sutton, Brad
• Dye, Matthew

• Neuroscience
• Anatomy
• Aging
• Cerebrovascular
• Fletcher
• Fitness

Statement dc:rights

• Copyright 2017 Mark Allen Fletcher

Language dc:language

en

Handle dc:identifier

http://hdl.handle.net/2142/98210

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/98210