{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/98210"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/98210","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Brain anatomy: investigations of the effects of aging, fitness, and arterial stiffness","abstract":"This work explores the mechanisms and lifestyle modifiers of brain anatomy throughout the aging process. First, a thorough review of the mechanisms of fitness on brain anatomy is presented. Next, a study examining the effects of aging and fitness on cortical and subcortical brain anatomy in a group of older adults (55-87 years old) is presented. We examine the degree to which cortical, subcortical, and global volumes are sensitive to both age and fitness. Lastly, the effect of cerebrovascular stiffness on the anatomical difference between and within individual subjects is explored across the lifespan (18-75 years old).","abstract_html":"This work explores the mechanisms and lifestyle modifiers of brain anatomy throughout the aging process. First, a thorough review of the mechanisms of fitness on brain anatomy is presented. Next, a study examining the effects of aging and fitness on cortical and subcortical brain anatomy in a group of older adults (55-87 years old) is presented. We examine the degree to which cortical, subcortical, and global volumes are sensitive to both age and fitness. Lastly, the effect of cerebrovascular stiffness on the anatomical difference between and within individual subjects is explored across the lifespan (18-75 years old).","abstract_has_math":false,"creators":["Fletcher, Mark Allen"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Neuroscience","degree_department":null,"school":null,"contributors":["Fabiani, Monica","Gratton, Gabriele","Sutton, Brad","Dye, Matthew"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2017,"date_issued":"2017-09-29T16:38:59Z","date_published":"2017-09-29T16:38:59Z","updated_at":"2026-07-22T22:24:35Z","subjects":["Neuroscience","Anatomy","Aging","Cerebrovascular","Fletcher","Fitness"],"languages":["en"],"rights":["Copyright 2017 Mark Allen Fletcher"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/2142/98210","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Fabiani, Monica","Gratton, Gabriele","Sutton, Brad","Dye, Matthew"]},{"key":"dc:creator","label":"Author","values":["Fletcher, Mark Allen"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2017-09-29T16:38:59Z","2019-09-30T09:15:08Z","2017-05-19","2017-08"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Neuroscience"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Neuroscience","Anatomy","Aging","Cerebrovascular","Fletcher","Fitness"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2017 Mark Allen Fletcher"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/98210"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["This work explores the mechanisms and lifestyle modifiers of brain anatomy throughout the aging process. 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Lastly, the effect of cerebrovascular stiffness on the anatomical difference between and within individual subjects is explored across the lifespan (18-75 years old).","Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2019-08-01","The student, Mark Fletcher, accepted the attached license on 2017-04-28 at 15:17.","The student, Mark Fletcher, submitted this Dissertation for approval on 2017-04-28 at 15:32.","This Dissertation was approved for publication on 2017-05-19 at 12:53.","DSpace SAF Submission Ingestion Package generated from Vireo submission #11141 on 2017-09-29 at 11:13:01","Made available in DSpace on 2017-09-29T16:38:59Z (GMT). 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First, a thorough review of the mechanisms of fitness on brain anatomy is presented. Next, a study examining the effects of aging and fitness on cortical and subcortical brain anatomy in a group of older adults (55-87 years old) is presented. We examine the degree to which cortical, subcortical, and global volumes are sensitive to both age and fitness. Lastly, the effect of cerebrovascular stiffness on the anatomical difference between and within individual subjects is explored across the lifespan (18-75 years old).","Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2019-08-01","The student, Mark Fletcher, accepted the attached license on 2017-04-28 at 15:17.","The student, Mark Fletcher, submitted this Dissertation for approval on 2017-04-28 at 15:32.","This Dissertation was approved for publication on 2017-05-19 at 12:53.","DSpace SAF Submission Ingestion Package generated from Vireo submission #11141 on 2017-09-29 at 11:13:01","Made available in DSpace on 2017-09-29T16:38:59Z (GMT). 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