Diffusion and Magnetization Transfer Studies of Neural Tissue

Our experiments showed that diffusion and magnetization transfer do not offer a unique window to neural function, as had been suggested by some reports in the literature. Rather, our studies taken together with the literature suggest that both these phenomena affect the standard hemodynamics-dependent functional MRI signal. The work presented here therefore helps to understand previously reported observations about diffusion and magnetization transfer. En route to testing the possibility of using diffusion imaging to image neural function, a new apparent diffusion tensor (ADT) imaging pulse sequence was developed and tested, and better insight into the measurement of the ADT was reached using both experiments and simulations.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Physiology

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2015

Author dc:creator

• Gulani, Vikas

Contributors dc:contributor

• Lauterbur, Paul C.

• Biology, Animal Physiology

Language dc:language

eng

Identifier

(MiAaPQ)AAI9912248

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/87266