Back to results
University of Illinois at Urbana-Champaign
Isolation and Characterization of Novel Estrogen Binding Proteins: Physiological Implications
Abstract
dc:descriptionIn summary, I have demonstrated the effect of estrogen and estrogen-like compounds on mitochondrial membrane-bound F0F1-ATPase and my efforts to isolate and identify cell membrane estrogen receptor have led me to discover a novel physiologically relevant estrogen binding protein: tubulin. Tubulin shows high affinity for estradiol and for testosterone, and these two steroid hormones modulate microtubule polymerization in an opposite manner. These findings add new information to our understanding of the non-genomic effects of steroid hormones mediated through those two novel estrogen/testosterone binding proteins.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Molecular and Integrative Physiology
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2015
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Kipp, Jingjing Liu
- Contributors dc:contributor
-
- Ramirez, Victor D.
Subjects
dc:subject × 1Rights
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
- (MiAaPQ)AAI3070015
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/87218