Back to results
University of Illinois at Urbana-Champaign
Evaluation of Metabolic Endpoints for Use as Biomarkers of Exposure to Environmental Estrogens and in Bioassays of Their Activity
Abstract
dc:descriptionThese findings indicate that angiotensinogen and uterine complement C3 can serve as sensitive indicators of estrogenicity. Additionally, angiotensinogen has the potential to be a biomarker of exposure to estrogenic compounds because its measurement only requires a blood sample, while providing a sensitive biochemical endpoint to supplement the uterotrophic assay. Nevertheless, other endpoints that can be used as potential biomarkers of environmental estrogen exposure are still needed since angiotensinogen is not specific to estrogens and thus cannot be used alone.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Biology
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2015
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Dean-Colomb, Windy
- Contributors dc:contributor
-
- Jeffery, Elizabeth H.
Subjects
dc:subject × 1Rights
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
- (MiAaPQ)AAI3130907
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/85351