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University of Illinois at Urbana-Champaign
Modified Farnesyl Diphosphate, Germacrane, and Eremophilane Sesquiterpenes as Probes for Capsidiol *Biosynthesis
Abstract
dc:descriptionThe final part of this thesis discusses the preparation and characterization of two deoxycapsidiols as well as a series of capsidiol analogs including epiaristolochene and two isomers. Overall, ten capsidiol derivatives were synthesized from capsidiol and sent to collaborators for various biological evaluations. In addition, this library was evaluated for antifungal activity in order to establish preliminary structure-activity relationships.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Chemistry
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2015
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Zhao, Yuxin
- Contributors dc:contributor
-
- Coates, Robert M.
Subjects
dc:subject × 1Rights
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
- (MiAaPQ)AAI3199199
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/84208