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University of Illinois at Urbana-Champaign
Direct Analysis of Intact Proteins From Microorganisms Using Top Down Mass Spectrometry
Abstract
dc:descriptionWe applied this top down proteomics platform to study proteins from Methanococcus jannaschii and Saccharomyces cerevisiae. From the whole cell lysate of yeast, ∼120 ion species were successfully identified with 100% sequence coverage, and we also detected several post-translational modifications, including acetylations, phosphorylations, methylations, formylations and oxidations.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Chemistry
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2015
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Meng, Fanyu
- Contributors dc:contributor
-
- Kelleher, Neil L.
Subjects
dc:subject × 1Rights
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
- (MiAaPQ)AAI3111620
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/84127