Design, Fabrication, and Test of Chaotic Micromixers, Hydrogel Microvalves and pH Regulation Systems

In the last part of the thesis, two integrated microsystems designed to provide self regulation of pH in bioassays are demonstrated. The first system is based on the counterflow microdialysis principle, whereas the second system involves direct addition of an acidic or basic buffer solution into a sample solution. In both systems, a hydrogel component is used as a pH sensor, controller, and valve, simultaneously. Oscillatory modulation of the flow was achieved, and the feasibility of autonomous control of pH in microsystems has been demonstrated.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Mechanical Engineering

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2015

Author dc:creator

• Liu, Hui

Contributors dc:contributor

• David J. Beebe

• Engineering, Mechanical

Language dc:language

eng

Identifier

(MiAaPQ)AAI9996655

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/84016