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University of Illinois at Urbana-Champaign
Engineering and Characterization of a Single Chain Antibody Specific for Murine CD28
Abstract
dc:descriptionFinally, a novel method of measuring the thermal stability of engineered antibody fragments using yeast surface display and flow cytometry was produced. This method allowed for the rapid determination of relative temperature stability without the need to produce large quantities of protein. This method compared favorably to other methods relying on soluble proteins and will facilitate the engineering and characterization recombinant proteins in the future.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Neuroscience
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2015
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Orr, Brent Alan
- Contributors dc:contributor
-
- Roy, Edward J.
Subjects
dc:subject × 1Rights
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
- (MiAaPQ)AAI3269995
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/82515