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University of Illinois at Urbana-Champaign
Microblood Analyzers for the Sensitive and Portable Detection of Clinically Relevant Cardiac Markers
Abstract
dc:descriptionA laminar tube flow with 1st order wall reaction model was used for the cFABP microdevice assay, which could predict assay behavior for a range of conditions. The pseudo-first order reaction rate was estimated at ∼1.5x10-6 m/s, and it was determined that a 40 mum wide channel operated in the desirable reaction rate limited regime, rather than the undesirable mass transfer limited regime of conventional heterogeneous immunoassays. The model also provided reasonable estimates of assay sensitivity (0.5 pg/mL--600 pg/mL depending on the assay parameters).
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Chemical Engineering
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2015
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Larsen, Robert T.
- Contributors dc:contributor
-
- Masel, Richard I.
Subjects
dc:subject × 1Rights
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
- (MiAaPQ)AAI3290461
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/82403