Abstract
dc:descriptionLarge-scale integrated microfluidic networks were designed and fabricated in order to carry out large combinatorial synthesis and screening. The microfluidic devices contained a series of small chambers with a total volume of one nanoliter to contain each of the combinations in the screening library. The library screen was carried out using a label-free sensor that was integrated into the microfluidic device. The sensor identified strongly binding ligands in a combinatorial screen of antibodies.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Chemical and Biomolecular Engineering
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2015
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Toepke, Michael W.
- Contributors dc:contributor
-
- Kenis, Paul J.A.
Subjects
dc:subject × 1Rights
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
- (MiAaPQ)AAI3243012
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/82389