Hybrid Micro/nanofluidic Sampling Schemes for Mass Spectrometry

Novel analytical sampling techniques are investigated in an effort to advance the exploration of chemical reactions underlying life processes. The analysis of substances found in living organisms is challenging and includes the precise collection, preparation, and identification of complex biological samples. An appropriate sampling scheme simplifies the collection, as well as the pretreatment procedures in order to allow for more direct chemical analyses. Here, hybrid micro/nanofluidic manipulation schemes are explored and interfaced with mass spectrometry in the effort to study the distribution and dynamic release of neurotransmitters and neuropeptides from individual neurons.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Chemistry

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2014

Author dc:creator

• Iannacone, Jamie Marie

Contributors dc:contributor

• Sweedler, Jonathan V.

• Chemistry, Analytical

Identifier

(UMI)AAI3314801

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/72243