Effect of Therapeutic Intervention on Pathophysiology, Pathology, and Survival in Rats and Swine Following Acute Intravenous Exposure to T-2 Toxin

Rats and swine were used to assess the efficacy of a number of drugs for the treatment of acute T-2 toxicosis induced by the intravenous administration of lethal doses of T-2 toxin. In rats, efficacy was assessed by analysis of survival times and rates and the severity of histologic tissue lesions in target organs. In swine, efficacy was assessed by analysis of survival times and rates and changes in physiologic parameters.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Veterinary Medical Science

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2014

Author dc:creator

• Poppenga, Robert Howard

Contributors dc:contributor

• Buck, William B.

• Biology, Veterinary Science

Identifier

(UMI)AAI8803170

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/71349