Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 349 for “"therapeutic intervention"”.
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Therapeutic intervention with children: types and determinants
… explored the types and determinants of psychotherapeutic intervention with children. The sample consisted of 76 licensed professionals in the fields of psychology, social work, and counseling. Family therapy was the preferred type of psychotherapy; however, psychotherapists employed different …
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Post-translational modifications of c-FLIP: opportunities for therapeutic intervention
… not. Targeting FLIP in cancer is an attractive therapeutic approach, though due to its lack of enzymatic activity strategies have remained elusive.<br/><br/> A tissue microarray study performed on 184 samples from non-small cell lung cancer patients revealed that FLIP and procaspase-8 are both …
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Hdm2 Small-Molecule Inhibitors For Therapeutic Intervention In B-Cell Lymphoma
… lymphoma is a suitable model for studying therapeutic value of disrupting HDM2-p53 association by small-molecule inhibitors (SMIs). HDM2 SMIs have been developed and are currently under various stages of preclinical and clinical investigation. This study examined various molecular …
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Art Used as a Therapeutic Intervention Between Isralie Arabs and Jews
… between these two ethnic groups. Among the many interventions being employed by these organizations is the use of art. This qualitative study, conducted in Israel at the three organizations cited above, describes how art is used as a therapeutic intervention between Israeli Arabs and Jews. It …
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The Effects of a Novel Therapeutic Intervention in Diabetic Peripheral Neuropathy Patients
… this study is to look at the impact of a novel intervention called Intraneual facilitation (INF) on objective static, objective dynamic, subjective balance measures, and a peripheral neuropathy scale in patients with Diabetic Peripheral Neuropathy (DPN).</p> <p>Balance will be assessed using VSR …
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Computational analysis of biochemical networks for drug target identification and therapeutic intervention design
… network. We quantify a relationship between how interventions at different places in network affect an output of interest. We use this quantitative relationship between target inhibited and output of interest as a metric to compare targets. In network analyzed here, most targets show a sub-linear …
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Combating Plague: Fighting a War on Two Fronts Through Vaccine Design and New Therapeutic Intervention
… occur annually. With no FDA-approved vaccine and therapeutics limited to antibiotics, there is an imperative need to develop new prophylactics as well as therapeutics against plague infection. Identification of new virulence factors of Y. pestis and understanding their role during the infection …
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Differential Activity of The Kras Oncogene By Method of Activation: Implications For Signaling and Therapeutic Intervention
<p>Despite having been identified over thirty years ago and definitively established as having a critical role in driving tumor growth and predicting for resistance to therapy, the <em>KRAS</em> oncogene remains a target in cancer for which there is no effective treatment. KRas is activated b y …
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Non-motor symptoms in the aav-α-synuclein rat model of Parkinson’s disease: exercise as a therapeutic intervention
Parkinson’s disease (PD) is no longer primarily classified as a motor disorder due to the emergence of a number of non-motor symptoms (NMS) of the disease. These NMS are highly prevalent and greatly affect the quality of life of patients with PD. Thus, an animal model that replicates these symptoms …
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Targeting the adenosine pathway reshapes a myeloid-dependent tumour microenvironment in pancreatic ductal adenocarcinoma. An opportunity for therapeutic intervention
Background: The prognosis for patients with pancreatic ductal adenocarcinoma (PDAC) remains extremely poor with less than 10% of patients surviving more than 5 years from the diagnosis. PDAC is considered relatively resistant to conventional therapies and recently lack of efficacy of immunotherapy …
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Molecular Modeling of the Amyloid β-Peptide: Understanding the Mechanism of Alzheimer's Disease and the Potential for Therapeutic Intervention
… the chemical features that give rise to this therapeutic effect.
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On the Role of Polyamines and Microvesicles in Tumour Development. Regulation by Hypoxia and Implications for Therapeutic Intervention of Cancer.
… tumour-derived MVs as promising candidates for therapeutic intervention or as biomarkers of cancer disease.
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Exploring the psychological effects and emotional reactions of mothers to their children's burn injury : aiming at proposed future therapeutic intervention
… have only been a few reported psychological interventions to assist mothers in helping them emotionally to support their injured child and family, as well as to assist them over the traumatic period. This study aims at investigating these issues and at initiating proposed future therapeutic …
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Effect of Therapeutic Intervention on Pathophysiology, Pathology, and Survival in Rats and Swine Following Acute Intravenous Exposure to T-2 Toxin
Rats and swine were used to assess the efficacy of a number of drugs for the treatment of acute T-2 toxicosis induced by the intravenous administration of lethal doses of T-2 toxin. In rats, efficacy was assessed by analysis of survival times and rates and the severity of histologic tissue lesions …
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Music and its meaning: an interpretative phenomenological analysis of the experience of chronic pain sufferers use of music as a therapeutic intervention
… self-selected music-listening is a documented therapeutic intervention that offers the potential to improve psychological and physical well-being in chronic pain sufferers. Aims The aim of this thesis was to explore how chronic pain sufferers experience and make sense of listening to music …
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Y-box binding protein-1 (YB-1) is a bio-marker of aggressiveness in breast cancer and is a potential target for therapeutic intervention
… that targeting YB-1 may provide a new avenue for therapeutic intervention in these breast cancers that are currently challenging to treat. Cox regression multivariate analysis indicates that YB-1 is second only to nodal status as a strong independent prognostic marker for poor outcome and relapse …
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The development and evaluation of the Cognitive Behavioural Social Competence Therapeutic Intervention for Adults with Autism Spectrum Disorder without an Intellectual Disability (CBSCTI-ASD)
… into adulthood, evidence-based social skills interventions to support individuals with ASD during this transition are rather limited. There is growing evidence to suggest that social competencies in adults with ASD without an intellectual disability (ID) can be enhanced through both individual …
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"Now there are no rules" : boundary activity in a psychoanalytically run-group therapeutic intervention for adolescent boys with learning difficulties : a case study exploration
This dissertation attempts to investigate by way of analysis of clinical material, a traditional psychoanalytic approach to working in a group with severely troubled adolescents with learning difficulties. The study is located within a theoretical context of an understanding of adolescent male …
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