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University of Illinois at Urbana-Champaign
Nitroxide Spin Labels as NMR Contrast Agents: Delivery, Metabolism and Relaxation
Abstract
dc:descriptionIn this project, the potential of nitroxides as contrast agents for magnetic resonance imaging (MRI) has been studied. The difficulties involved in using nitroxides as in vivo MRI contrast agents, such as premature metabolic convertion of nitroxides to their nonparamagnetic state, lack of tissue selectivity, and relatively low relaxivity of nitroxides, were, in part, overcome by the use of liposomes as the delivery system.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Biophysics
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2014
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Chan, Hsiao Chang
- Contributors dc:contributor
-
- Magin, Richard
- Swartz, Harold M.
Subjects
dc:subject × 1Identifiers
dc:identifier.*- Identifier
- (UMI)AAI8908643
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/70716