Biosynthesis of Selected Antibiotics

The biosynthetic pathway for the novel antibiotics nodusmicin (9) and nargenicin (10) was established as polyketide in origin. Three metabolites previously unreported from Nocardia argetinensis var. Huang (ATCC 31306) were isolated and identified as 18-O-acetylnodusmicin (13), and 18-O-acetylnargenicin (14).

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Chemistry

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2014

Author dc:creator

• Snyder, William Chapin

• Chemistry, Organic
• Chemistry, Pharmaceutical

Identifier

(UMI)AAI8803206

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/70395