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University of Illinois at Urbana-Champaign
The Delayed Neurotoxicity of Thio-, Allylthio- and Dithio-Carbamates and Its Relevance to a Mode of Action
Abstract
dc:description34 aryl carbamates which were synthesized in the laboratory and 4 commercial carbamates, were screened for delayed neurotoxicity in the White Leghorn hen. Several carbamates proved to be delayed neurotoxins with this ability being particularly concentrated in the thiocarbamates bearing short, unbranched alkyl sidechains. The toxicity of these compounds was further examined in Musca domestica (LD(,50)) and Culex quinquefasciatus (LC(,50)) to discern correlations between esterase inhibition and delayed neurotoxicity.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Entomology
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2014
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Wesley, Susan Warwick
Subjects
dc:subject × 1Rights
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
- (UMI)AAI8127731
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/68018