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University of Illinois at Urbana-Champaign

Studies of Reaction Mechanisms Requiring Low Molecular Weight Thiol Cofactors

Abstract

dc:description

The methyl-transfer reaction between methylcobalamin and 2-mercapto-ethanesulfonic acid (Coenzyme M) was investigated. We propose that this reaction is a thiyl radical promoted homolytic cleavage of the cobalt-carbon bond rather than the nucleophilic attack by thiolate anion which has been pro

Degree

thesis:*
Name thesis:degree_name
Ph.D.
Level thesis:degree_level
Dissertation
Discipline thesis:degree_discipline
Biochemistry
Grantor
University of Illinois at Urbana-Champaign
Year dc:date
2014

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Frick, Thomas Dennison

Subjects

dc:subject × 1

Rights

Language dc:language
eng

Identifiers

dc:identifier.*
Identifier
(UMI)AAI8108506
OAI identifier oai:identifier
oai:www.ideals.illinois.edu:2142/67402

Chain of custody

source
Harvested from
University of Illinois - Urbana-Champaign
Base URL
www.ideals.illinois.edu/oai-pmh
Last updated
2026-07-22
Source record
OAI-PMH GetRecord
citation

Frick, Thomas Dennison. Studies of Reaction Mechanisms Requiring Low Molecular Weight Thiol Cofactors. Dissertation thesis, University of Illinois at Urbana-Champaign, 2014. http://hdl.handle.net/2142/67402