A Computational - Experimental Study of Small Globular Proteins

The folding of small globular proteins is studied using a combination of experimental and computational techniques. The use of several experimental probes to study the formation of secondary and tertiary structure of proteins is stressed to obtain a description of their folding. Molecular dynamics simulations are carried out under non-physiological conditions to overcome experimental obstacles. Under physiological conditions, the combination of molecular dynamics and experiments resolves the folding of small proteins in great detail.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Physics

Year dc:date

2012

Author dc:creator

• Larios, Edgar

Contributors dc:contributor

• Martin Gruebele

• Hyperfluorescent proteins
• ubiquitin mutants
• partially folded proteins

Statement dc:rights

• ©2005 Edgar Larios

Language dc:language

en

Identifier

5290866

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/34778