UV light inactivation of adenovirus, coxsackievirus and murine norovirus

The overall objective of this research project is to evaluate the efficiency of low-pressure (LP) and medium-pressure (MP) UV light irradiation to inactivate waterborne pathogens that are an increasing concern in drinking water. The inactivation of pathogens depends directly on the total UV dose or fluence (UV intensity multiplied by contact time) received by the microorganism. UV light irradiation is a treatment technology that relies on the inactivation of microorganisms by inducing genomic damage. However the results obtained in this research suggest that different wavelengths emitted by the medium-pressure UV source may be affecting not only the genome of the virus, but also proteins in the viral capsid that may disturb the ability of the virus to attach to the host cell and therefore its ability to complete its infection cycle. The conditions of the water used for the experimental work were modeled after those encountered at the Neuilly sur Marne water treatment plant in France.

Name thesis:degree_name

M.S.

Level thesis:degree_level

Thesis

Discipline thesis:degree_discipline

Environ Engr in Civil Engr

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2012

Author dc:creator

• Vazquez Bravo, Bernardo

Contributors dc:contributor

• Mariñas, Benito J.

• Inactivation kinetics
• Coxsackievirus
• Murine Norovirus
• Adenovirus

Statement dc:rights

• Copyright 2011 Bernardo Vazquez Bravo

Language dc:language

en

Handle dc:identifier

http://hdl.handle.net/2142/29534

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/29534