Genetic analysis of the proteins required for site-specific recombination of bacteriophage lambda: Interactions with each other and their recognition sites

In order to study the importance of the individual Int arm-type binding sites in $\lambda$ site-specific recombination, triple-base changes were made in each of the five Int arm-type binding sites, and then characterized through in vitro and in vivo recombination assays. These mutants demonstrated that the P1, P$\sp\prime$2, P$\sp\prime$3, and possibly the P$\sp\prime$1 sites are required for integration, while the P2, P$\sp\prime$1, and P$\sp\prime$2 sites are important for excision.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Biology, Molecular

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2011

Author dc:creator

• Numrych, Thomas Edward

Contributors dc:contributor

• Gardner, Jeffrey F.

• Biology, Molecular
• Biology, Microbiology

Statement dc:rights

• Copyright 1992 Numrych, Thomas Edward

Language dc:language

eng

Identifier

AAI9236555
(UMI)AAI9236555

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/23534