Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 117 for “"INT"”.
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The Role of Behavioral Mind-Sets on Auditors' Professional Skepticism: An Experimental Investigation of Auditor Int
… professional guidance urges auditors to maintain a skeptical mind-set since management's financial reporting incentives may lead to instances when it attempts to persuade the auditor into accepting a preferred accounting treatment. This study investigates how auditors' behavior when …
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Characterization of an Inhibitory Pathway to Feeding Command Neurons in the Brain of Pleurobranchaea Californica and an Analysis of the Changes in This Pathway That Occur as a Result of Food-Avoidance Conditioning
… pathway consists of 3 serially connected interneurons. The first population, the Interneuron 1s (Int-1s), mono-synaptically inhibits the PCNs. A second population, the Interneuron 2s (Int-2s) excite the Int-1s. A third population, the Interneuron 3s (Int-3s), mono-synaptically excites the …
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Analysis of Structure-Function Relationships in *Lambda and HK022 Site -Specific Recombination
… relationships pertaining to the Lambda and HK022 Integrase proteins (Int). First, homology-based modeling was used to create a three-dimensional model of the Lambda Int core-binding (CB) domain. The model suggests that all prokaryotic Tyrosine recombinases share a common CB domain fold, and …
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Genetic and mechanistic studies of the bacteriophage lambda integrase protein
… higher-order nucleoprotein complexes, called ""intasomes"", followed by a series of steps catalyzed by the phage-encoded integrase (Int). In order to study the functions of Int during recombination, Int mutants defective in in vivo excision were isolated and screened for proficiency in binding …
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Mutational analysis of integrase and excisionase proteins in bacteriophage lambda site-specific recombination system
… were performed on 21 recombination defective Int mutants. A second-site revertant P243L/E218K and a pseudorevertant E175K were isolated and further characterized using genetic and biochemical methods. The results showed that the second-site substitution E218K selectively enhances Int …
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Coordination and Catalysis of the Lambda Integrase Site -Specific Recombination Reaction
… the maximal cleavage and ligation activity of Integrase. From this work, we concluded that para-Nitrophenol tyrosine analogs are optimal for quantitative in vitro measurement of Int ligation. Int could not utilize tyrosine analogs para-Cresol and dimethyl- p-phenylenediamine as ligation …
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Temporal Dynamics at the Neurobehavioral Interface: In Search of a Common Currency
… of timescales in its neural activity, the Intrinsic Neural Timescales (INT) which are manifest in both time and frequency domain. However, the relationship of the brain’s INT to the varied timescales of behavior remains unclear. I investigate the dynamics of INT by measuring the median …
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A genetic analysis of bacteriophage lambda integrase-core site interactions
… utilizes a site-specific recombination system to integrate its DNA into the E. coli chromosome during lysogeny. The viral protein, Integrase (Int), catalyzes strand exchange between the phage attachment site, attP, and the host target sequence, attB to generate the prophage sites, attL and attR. …
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The Effect of Training Volume and Intensity on Improvements in Muscular Strength and Size in Resistance-trained Men
… and size are influenced by the volume and intensity of a resistance training program. While it is clearly advantageous for resistance-trained individuals to utilize programming specific to these goals, it not clear which is more important. Therefore the purpose of the present investigation …
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The Integration and Excision Mechanisms of the Bacteroides Conjugative Transposon CTnDOT
… system. Using the partial-purified CTnDOT Int protein, an in vitro integration system was developed and a host factor(s) from Bacteroides cell extract was shown to be important for integration. The CTnDOT Int protein catalyzes the in vitro integration reactions by a coupling sequence …
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Genetic analysis of the proteins required for site-specific recombination of bacteriophage lambda: Interactions with each other and their recognition sites
… order to study the importance of the individual Int arm-type binding sites in $\lambda$ site-specific recombination, triple-base changes were made in each of the five Int arm-type binding sites, and then characterized through in vitro and in vivo recombination assays. These mutants demonstrated …
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The Effect of Intranasal Oxytocin on Neural Functioning in Widow(er)s
The interplay between approach and avoidance in the bereavement process is central to conceptual models of complicated grief (CG), a persistent and unremitting form of acute grief. Oscillation between these motivation systems is thought to maintain maladaptive cognitive and behavioral patterns, …
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Detection and measurement of stress hormones with mass spectrometry
… three different training sessions; including an interval session (INT), tempo run (TEMP) and aerobic circuit training (CIR). An LC-MS method was developed to measure cortisol and testosterone. The mass spectrometer used was a triple quadrupole BioQ (Waters/Micromass, UK) coupled with a 1200 …
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Characterization of the Intrinsic Neural Timescale Indices as a Reliable Fingerprint of Brain Dynamics
<p>Intrinsic neural timescales (INTs) characterize the persistence of neural activity over time and offer insight into the brain’s temporal hierarchy. This thesis evaluates and compares six autocorrelation-based INT metrics—AR(1) Coefficient (Autoregressive Coefficient at 1), First Zero Lag, Lag at …
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Characterization of the Gifsy-1 Phage Excisionase
… serovar Typhimurium. During lysogeny, the phage integrates site-specifically into a single bacterial attachment sequence in the Salmonella chromosome. The reaction involves recombination between the phage attachment sequence (attP) and the bacterial attachment sequence (attB). The phage encoded …
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Calcium, actin and the spectrin skeleton: Responses to swelling and shrinking perturbations.
… calcium dependent exocytosis, then (Ca) $\rm\sb{int}$ rather than membrane tension may be the primary signal used in surface area regulation. (Ca) $\rm\sb{int}$ in swelling molluscan neurons was measured by FURA-2 ratiometric microscopy using perturbations which induced vacuole-like dilations …
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Determination of Thymic Epithelial Cell Composition and Proliferation During The Perinatal to Adult Transition
… RB family members or expression of cyclin D1 maintains perinatal-like TEC proliferation and continued thymus expansion.</p> <p>Although both cortical TEC (cTEC) and medullary TEC (mTEC) are expanded in the K5.D1 thymus, FACs analysis revealed a marked increase in a novel UEA-1<sup>int</sup> …
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Theory and applications of a functional from metric geometry
… $\nu$ on R$\sp{n}$, define $J\sp\alpha(\mu,\nu)=\int\int\vert x-y\vert\sp\alpha\ d\mu(x)d\bar \nu(y)$. Study of the energy integral $J\sp\alpha$ has its roots in metric embedding theory and potential theory. Subject to certain moment vanishing conditions, a representation formula is proved using …
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The role of AcrA in the antibiotic resistance and virulence of Salmonella enterica serovar Typhimurium
… the ability of S. Typhimurium to infect INT-407 and RAW 264.7 cells \(in vitro\) as previously published for AcrB and TolC mutants. The virulence defect of the mutants could not be rescued by addition of supernatant from an infection of INT-407 cells with SL1344 or addition of media …
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Identification and Characterisation of the Barley Row-Type Gene <i>VRS3 </i>
… at three loci, <i>VRS1</i>, <i>VRS4</i> and <i>INT-C</i>. Advancements in the understanding of the genetic control underpinning barley row-type enables the identification of potential mechanisms for improving yield and yield architecture within the cereals. <br/>This study used genetic linkage …
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