Comparative fates of three structurally distinct PCB congeners in rats and house flies

The toxicity, biotransformation and biological activities of polychlorinated biphenyls (PCBs) are influenced by the number and position of chlorine atoms on the biphenyl rings. The excretion and tissue retention of three $\sp{14}$C-labeled structurally distinct lower chlorinated PCBs (2,2$\sp\prime$,5-tri-, 2,2$\sp\prime$,4,4$\sp\prime$-tetra- and 3,3$\sp\prime$,4,4$\sp\prime$-tetrachlorobiphenyls) were examined in prepubertal (24-day old) rats following iv injection into the tail vein. Toxicokinetics and enzyme-related toxicities of these PCBs were also examined in female house flies following topical application.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Veterinary Medicine

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2011

Author dc:creator

• Saghir, Shakil Ahmed

Contributors dc:contributor

• Hansen, Larry G.

• Health Sciences, Toxicology
• Health Sciences, Pharmacology
• Environmental Sciences

Statement dc:rights

• Copyright 1994 Saghir, Shakil Ahmed

Language dc:language

eng

Identifier

AAI9512538
(UMI)AAI9512538

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/23280