Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 254 for “"FATES"”.
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The alternative evolutionary fates of mitochondrial proteins
Contains fulltext : 178927.pdf (Publisher’s version ) (Open Access)
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Hypoxia signalling regulates human lung epithelial cell fates
Human embryos develop in an environment with low oxygen tension (< 5% O2) during the first trimester. Hypoxia substantially impacts mammalian development and tissue homeostasis. However, it remains unclear whether and how hypoxia directly affects human lung epithelial development. In this PhD …
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Connecting consumer plastic formulations to marine fates and impacts
… mixture of polymers and additives) to marine fates and impacts. First, I explored relationships between consumer polyethylene (PE) bag formulations, degradation by sunlight, and dissolved organic carbon (DOC) release to seawater. I found that the bags contained 15-36% inorganic additives, …
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Connecting Consumer Plastic Formulations to Marine Fates and Impacts
… mixture of polymers and additives) to marine fates and impacts. First, I explored relationships between consumer polyethylene (PE) bag formulations, degradation by sunlight, and dissolved organic carbon (DOC) release to seawater. I found that the bags contained 15-36% inorganic additives, …
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Thewingless Signaling Pathway Specifies Fates in the Drosophila Embryonic CNS
The secreted proto-oncogene Wnt-1/Wingless (Wg) functions as an intercellular signaling molecule in many developmental processes. Studies in Drosophila have revealed that wg encodes positional necessary to regulate segmental identity during embryogenesis. This thesis examines the function of the …
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Pioneer Factors Compete for Epigenetic Factors in Switching Stem Cell Fates
… transcriptional activators or repressors of cell fates by recruiting co-activators or co-repressors. Nevertheless, whether and how a single factor can simultaneously silence the old fate while activating the new cell fate remains largely unknown. Here, I tackled this question with SOX9, a master …
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The sources and fates of nutrients in the Deep Lake watershed
… water quality survey determined the sources and fates of nutrients within the Deep Lake watershed located in Stevens County, WA. Deep Lake is a 191-acre exorheic lake found just below the Canadian border in northeast Washington state. It is situated at the bottom of a narrow valley with steep …
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The wingless signaling pathway specifies fates in the Drosophila embryonic CNS
The secreted proto-oncogene Wnt-1/Wingless (Wg) functions as an intercellular signaling molecule in many developmental processes. Studies in Drosophila have revealed that wg encodes positional necessary to regulate segmental identity during embryogenesis. This thesis examines the function of the …
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Why Cities Fail: Local Political Institutions and the Fates of Metropolitan Economies
What differentiates economically successful urban areas from those that fall into decline? This dissertation attempts to improve upon existing answers to this question by examining the relationship between metropolitan political institutions and local economic performance. The impetus for this …
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Α-HYDROXY FATTY ACIDS AND BIOPOLYMERS: NEW FATES FOR LIPID-ENRICHED FOOD SCRAPS
Biomasses deriving from food scraps represent a growing global issue, as they are hard to recycle and to dispose of. In this work, a new method for the implementation of food-related biomasses was assessed, in order to attain products via environment-friendly chemical processes. Food scraps may be …
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Studying the Patterning Mechanisms and Cell Fates during Limb Regeneration in Ambystoma mexicanum
We studied patterning mechanisms and cell fates during limb regeneration in the axolotl. 1) It is crucial to understand the earliest events of patterning. Since it is technically challenging to study early events, we established single cell PCR. This new tool will allow us to obtain novel insight …
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SGK196 controls stem cell fates by promoting the degradation of TGFβ family receptors
Much remains to be understood regarding the molecular mechanisms controlling stem cell fate. Through studies in human pluripotent stem cells (hPSCs), I have identified SGK196, an atypical kinase of relatively unknown function, as a novel regulator of cell fate and the TGFβ family signaling pathway. …
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Comparative fates of three structurally distinct PCB congeners in rats and house flies
The toxicity, biotransformation and biological activities of polychlorinated biphenyls (PCBs) are influenced by the number and position of chlorine atoms on the biphenyl rings. The excretion and tissue retention of three $\sp{14}$C-labeled structurally distinct lower chlorinated PCBs …
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Asymmetric localization of prospero and numb specifies cell fates in the Drosophila CNS
A central question in developmental biology is how can two genetically equivalent cells become different? Nowhere is this question more compelling than in the case of sibling cells, where each is derived from the single division of a parental cell. This thesis identifies two proteins involved in …
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Flows and fates of nickel-cadmium batteries in the City of Cape Town
Current patterns of economic activity entail high rates of material extraction from the natural environment and the generation of large amounts of waste. Alternative strategies must be found if we are to avoid the exhaustion of resources and the environment's capacity to safely absorb our wastes. …
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Fates of spilt oil and factors affecting the bio-degradation of oil: a review
… and bio-degradation along with other possible fates. Biodegradation is one of the most significant processes of weathering which depends on oil physical and chemical characteristics, environmental characteristics, pH, salinity and oil concentration. There is a range of oil concentration for …
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Insights into the rice and Arabidopsis genomes: intron fates, paralogs, and lineage-specific genes
<p>With the availability of near-complete rice genome sequence,</p> <p>high-quality annotation data, and large expression profile datasets, we examined</p> <p>segmental duplication, intron turnover, and paralogous protein family</p> <p>composition in rice. These data suggest a large percentage of …
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The fates of binary companions in Type Ia supernovae within the single-degenerate scenario
Type Ia supernovae (SNe~Ia) are thought to be caused by thermonuclear explosions of carbon-oxygen white dwarfs in close binary systems. However, the nature of the progenitor systems is still uncertain. In the single-degenerate scenario (SDS), the companion star is non-degenerate and can be …
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The synthetic multivulva genes and their suppressors regulate opposing cell fates through chromatin remodeling
… (synMuv) genes act redundantly to inhibit vulval fates in Caenorhabditis elegans. These genes are grouped into three classes called A, B and C. The class A genes encode putative transcription factors. The class B and C genes encode presumptive transcriptional repressors and chromatin-remodeling …
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