The structure of cyclic fatty acid monomers isolated from heated linseed oil and their effects on cultured aortic endothelial cells

This study reports the complete structural configuration of CFAM isolated from heated linseed oil and the influence of these components in cultured porcine aortic endothelial cells. Using CFAM-oxazoline derivatives, location of unsaturation and ring structures were confirmed using gas chromatography-matrix isolation-Fourier transform infrared spectroscopy and gas chromatography-mass spectrometry. The CFAM were identified as 18-carbon diunsaturated structures containing cyclopentenyl and cyclohexenyl rings in various positions along the molecule. One site of cis unsaturation was always within the ring structure while the other site of unsaturation was either cis or trans and could be located at various positions in either the carboxyl- or methyl-terminal chain of the ring. Three pairs were identified as cyclic stereoisomers.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Food Science and Human Nutrition

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2011

Author dc:creator

• Flickinger, Brent David

Contributors dc:contributor

• Perkins, Edward G.

• Biology, Cell
• Biology, Animal Physiology
• Health Sciences, Nutrition

Statement dc:rights

• Copyright 1995 Flickinger, Brent David

Language dc:language

eng

Identifier

AAI9543585
(UMI)AAI9543585

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/22783