Serial protein pairs in cell/surface adhesion

The theoretical and experimental work described offers the first systematic investigation of cell/surface adhesion mediated through protein/protein bonds in series. Cell adhesion and migration are facilitated through protein/protein bonds in series established when membrane-bound proteins simultaneously interact with extracellular proteins and with intracellular cytoskeletal components. The biotechnological application of affinity-based cell separation exploits serial protein/protein bonds to isolate a target cell type from a heterogeneous pool of cells.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Chemical and Biomolecular Engineering

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2011

Author dc:creator

• Saterbak, Ella Annette

Contributors dc:contributor

• Lauffenburger, Douglas A.

• Biology, Cell
• Engineering, Biomedical
• Engineering, Chemical
• Biophysics, General

Statement dc:rights

• Copyright 1995 Saterbak, Ella Annette

Language dc:language

eng

Identifier

AAI9624482
(UMI)AAI9624482

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/22406